Spin the wheel while holding a finger near the tire and see if the gap gets larger and smaller. If so, the next step is watching the rim in the brake shoes to see if it too rises and falls.
If the rim isn't round, you need a wheel alignment. OTOH if the rim is true or has much less eccentricity than the tire then you have a tire problem. Often it's a matter of poor seating, with on section deeper or higher in the rim. Confirming by spinning the wheel slowly and watching the molded lines nearest the rim. If the seating is OK but the tire isn't round or has a local bump, it's a warning sign that the cord is fractured and beginning to let go. This isn't repairable and calls for a new tire.
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