I use Shimano PD-M324 on my bicycle, so that I could use normal shoes for commuting (it's only 2 miles) but could clip in other times. I don't find it difficult to select which side to use--rather than being weighted so that one side is up or down, they're weighted so that the platform side faces forward and the clipless side faces backwards. So, it's very easy to orient.

Very occasionally the wrong side is up front, but it's not a big deal for me; I just pedal half a revolution and the other side is now up.

The other reason why I got the M324s has a bit to do with paranoia--these pedals take normal reflectors and I don't want some jackass saying that I was breaking committing some sort of technicality cycling at night without pedal reflectors and *that's* why they didn't see me despite lights and safety vest. I've never heard of anyone running into issues for not having pedal reflectors before, though, so I don't think it's a very credible concern.

The other nice thing (for me, at least) about the PD-M324s is that they come with the multi-directional release cleats. I've yet to fall from not being able to unclip despite several close calls where I forgot about being clipped in, and yet to unclip when I didn't want to.

As a related anecdote, I tried on about 6 shoes before settling on a pair of Shimano M087G's, which have treated me well so far.