Originally Posted by Minion1

Yep, most hubs come in a range of spoke hole drillings, so you match them to the number of spoke holes in the rims. You can mismatch but wouldn't recommend it at all, let alone on the first pair of wheels you build.

IMO buy a cheap pair of junkers off the bay and practice on them, see if it's for you.

Price will also be an enormous factor.

And yes, Dura achee, campa and DT Swiss are awesome. I've never had an incentive to throw down for Chris Kings but wheel nerds love them.