Hmm. Hmmmmmmm. Hmmm.
I'm riding a secondhand custom built frame made with really light weight tubing. Lately I've been able to put a lot of miles on in the past couple of weeks due to a "safer-than-sorrier" diagnosis from an urgent care doc. Almost every ride I nearly wet my pants with glee with how this frame is stiff in the right ways and handles gnarly chatter bumps and busted concrete.
I guess the point is, if you go for a non-custom high end frame you will be very happy. Go custom fitting and high end materials and you too will ride with the pants wet with glee.
If you're going to go, go all out. And don't forget the proofhide.
Don't want it stolen? Never stop riding.