Yesterday, 28F:

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Shimano MT21 + thin cycling socks + wool hiking socks = toasty warm feet
Today, 30F:

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Shimano MT21 + wool hiking socks = cold feet
I wore the cycling socks yesterday as a fungus barrier, since none of my wool socks were clean. I'm shocked how much difference they made.
As to what constitutes "cold" I think it depends on the climate in which you live. I grew up in the hills of western Maryland and I had no problem going out in sub-zero temperatures. After 15 years living in the PNW, anything below 32 is quite cold. Your body adapts, I guess. Or maybe I'm just getting old.