I have prescription glasses and I've seen a lot of other people say that they can't see in glasses when it's raining, but I've never found it to be an issue. I mean, it definitely makes it harder to see but I've never felt it dangerously so.
I have problems with my glasses fogging usually only when it's cold, and when I stop. Usually motion unfogs them. I've tried various sprays, etc. but haven't found anything that seems to make any difference so far.
I live with the fact that I'm going to get soaked; although I do wear a jacket when I know it's going to rain. I also just bought some O2 rain pants and tried them out this week. I think they helped some, but I would give them mixed reviews at this point.
I hang all my commute clothes up at work and even when I've ridden in a steady rain I've never had a problem with stuff not being dry by the time I go home.