I think the OP needs to clarify whether he wants Flat Resistant tires that still ride nicely (eg. Gatorskins, Armadillos, etc), or if he really wants to eliminate flats, which would require the Mr Tufffy Liners, the no-air tires, or solid rubber.

If he wants "the best" in performance and "the best" in flat resistance, the answer is nothing.

Sorry kid, that's life....it's all a tradeoff.