The CAAD 10 is a great do all bike, for either the recreational cyclist or the racer on a budget. I had a CAAD 9, with Rival and a BB30 crank. It was one of my favorite bikes. That said, I would have bought an S2 if I could have, but there was like a $1400 difference in the MSRP at the time.
The s2 and s5 are really race machines. Obviously you can do whatever you want with your money, and ride a $10,000 bike to the coffee shop.