Not for commuting, but if it's your only bike-perhaps. "Real" thieves can spot high end stuff no-matter how it's disguised. The key is to lock it equally, or better than everyone else.

I've a spare single speed "pub bike" that's quite randy, and not worth anything (except the hubs)-that I use if I'll be locking up on the street for an extended time.

For quick release skewers, you can swap them for bolt on ones (that use an allen wrench) through Nashbar/Performance relatively cheap. I'd probably lose the special wrenches that you need with security skewers (ie Kryptonite).