I have been running tubeless for about two years now (Campy Zonda 2-way fit wheels with Hutchinson Fusion tires). I love the ride at 90-100 psi, they roll and grip well, and I still haven't had a flat that the sealant hasn't ben able to seal (using Hutchinson sealant). I actually prefer the way they ride to my tubular tires (290 tpi with latex tubes).

My Fusion 2 tires weighed 307g each, for what it is worth.

With that said, there is a lot of information that can be found on this topic if you do a simple search in this forum, or on the web.