I use Carradice Super-C panniers, and love them. Took them on a tour of the California coast last winter when we had a serious of four sever storms. They are cotton duck, so are very sturdy, and I just waterproof them once a year, using the same stuff you would use for an oilskin jacket. So far I have had nothing inside get wet, and I ride in fairly wet environments. They are also not all that heavy and carry a good amount.
Work well with most rack combinations, and fit very snug with the Tubus rack I have.