Originally Posted by
mechBgon
Highly controversial subject, as with many facets of wheelbuilding
Some say "Bah! there should be no need for any sort of threadlock or lubrication, because reasons!" But if I don't fill those threads with something, Mother Nature will. And her favorite is road grit.
I've always used anti-seize and haven't had any problems with my alloy nipples turning freely and being reusable when it's time for a rim replacement.
Last year I swapped a Reflex Clincher installed when Mavic still made those (maybe 1997 or 1998 meaning the wheel had been exposed to rain and a little snow/road salt from Boulder, CO where I lived through 2006) for a new Open Pro without issue.