Originally Posted by hhnngg1

Yes, but unless the downhill section of the hilly route is safe enough to bomb down while cranking high cadence, you may have to sacrifice your aerobic workout on that section. As my prior post above, my hill route has 20 minutes of near zero pedaling since it's a very windy, narrow but steep descent. Close to zero workout effect on the descent.

On uphills, I definitely can get close to my maxHR on the hillier routes than the flat ones for whatever reason, but given that I don't try to stay in my max-HR zone for more than brief moments, it's kind of irrelevant.