I have a Giant Defy and bought it in July 2011 and have logged well over 2000 miles on it. I LOVEEEEEE it. I got it when I was 365 pounds so yes, it should be find for you. Now curb hopping! And be mindful of the back rim. I changed out tires to Gatorskins because bigger guys wear tires down faster plus it protects against glass. With thin tires, being a big guy and rolling over glass, factory tires suck. But you can use the factory ones until you need to switch.

I eventually broke spokes after a while in the back to I had them put on heavier and better quality spokes which were DT spokes. Cannot remember size or anything but find an OUTSTANDING place to sell you the Defy and talk with the owner or manager if you can. Sometimes the other workers do not know $hit about bikes for heavy people. Just my experience.

You will love the bike my friend!