Yep. My humble Accord gets 28 in the suburbs and 33 hwy, but it still hurts to the tune of $60 to fill it up now.
I suspect we'll see more scooterists and cyclists as gas prices continue to climb.
I currently and doing a multi-modal commute; bike-train-walk, so I'm still affected by gas prices in the form of the train tickets. I just did the math, and now that gas has topped $4.20 a gallon by me, I'm just saving about $40 a month on gas compared to driving.