I did a 80km ride on the Mezzo last weekend. I managed surprisingly well given I was the only person riding a folding bike. Got up to 68km/hr on some of the mountain downhills.

Unfortunately I got doored by someone getting out of a taxi while cycling back to my place. I didn't expect it to come from my left side.
Anyway, I'm fine and aside from some scrapes on my bar end the bike has no visible damage.
One thing I like about the Mezzo that hasn't been mentioned is that I was able to get a little more reach out of the bike by rolling the handlebar forward. Instead of acting like a riser it acts like a longer stem. This is nice given I'm bordering on too tall for the whole "one size fits all" thing.
I'd also say that the best upgrade I've added is a set of small ergon bar ends. I think the manual might technically say not to do this (covering themselves against lawsuit?) but I've had no problems and they're extremely helpful when climbing out of the saddle.