I could tell some stories here, so I will stick to the question at hand.
A glass or two of wine, while remaining properly hydrated, no problem for me. I used to keep a bottle of gator-aid on the night stand. When I got up in the middle of the night to visit the bathroom, I'd often chug the entire bottle. Woke up feeling fine.
One time (and I do mean, ONE time) I over did it with some bourbon. The next morning wasn't pleasant, I will assure you...
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'10 Specialized Hardrock