OP, I have two Giants, a TCR and an SCR C4. The SCR is the predecessor of the Defy in their range, slightly taller head tube and longer wheelbase than the TCR. As a result it is less twitchy than the TCR and has me in a fractionally more upright position. It's the bike I turn to for long-distance rides. The Defy geometry is very similar, I think, and as I'd expect it gets great reviews. I'm sure you wouldnt be disappointed with it.