Yes! I wear mine at night, and since I started, my pain has dropped considerably. What happens at night is that while you sleep, the tendons pull your hands down, and that aggravates the condition. The wrist straps prevent that, and things improve greatly.

One thing that I'd suggest is that you make sure that there's a tab on the velcro that you can use to get the velcro loose. It's kinda annoying when you need to take care of business and you can't get the damn brace off.