I have a CB Mule w/ 100 oz bag. I use it mostly off road. I prefer the bottles on road. However, there are some long road rides in the mountains of SoCal (like Azusa Canyon to Dawson Saddle) where food, water and assistance (if anything goes wrong) are just not available. So for those kinds of rides, I take the CB.

Also, CB offers insulated tube covers so your first sip is always cold.