Hmm these are what I would keep in mind:

- Which brand components am I most familiar with (for me, Shimano)
- Which one better has better ergonomics
- Which one has a better wheelset, saddle, cockpit, etc...
- Am I going to upgrade components?
- If yes, then it will depend on my favorite frame color.

A lot of it will be up to you. But the CAAD10 frame in general is a stellar frame, you'll love it.