It's not going to set up as easily as a road frame; it's not going to handle as well as a road frame; and it's not going to be as comfortable as a road frame.
You can do it, and it will work ok, but why would you want to?
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You could fall off a cliff and die.
You could get lost and die.
You could hit a tree and die.
OR YOU COULD STAY HOME AND FALL OFF THE COUCH AND DIE.