I was very pleasantly surprised by the Planet Bike ARS Competition (
http://ecom1.planetbike.com/5022.html). No health issues to report with stock saddles, but like you, read some stuff on non-cutout saddles and thought why risk it.
I was between the Planet Bike and some of the ISM saddles but went cheap and haven't regretted it. NO pressure up the middle from the first ride and now that my sit bones are used to it, very little thought about my saddle at all.
Disclaimer 1: I'm a short/moderate distance commuter (5 miles round trip) and utility rider, not long distance.
Disclaimer 2: It's your butt.