A guy I know well - Was having anxiety attacks that became more frequent.
He visited a psychologist for a while to "put to bed" his issues with his childhood. (Was abandoned by his parents and raised by paternal Grandparents) Once he decided to accept his biological parents as having been too young and stupid to raise a child and forgive them, that was solved. His problems dealing with people at work and associates was related to having problems with dealing with jerks. He found out that many people have that problem in some form. He found out how to blow-it-off and not dwell on things that are in the past, and how to recognize and identify people who are the ones who actually have the issues that bleed into his Karma. He said that one person in management with severe Narcissistic personality disorder was particularly difficult. Once he realized that this person was the problem and discovered how to properly deal with this, this was also solved.
He then gave up his daily marijuana use completely. (Said he had no problem quitting cold turkey after 30 years of being a heavy user)
Then he gave up the huge quantities of coffee he drank every morning into the afternoon. Went to a 100% caffeine-free lifestyle.
Not one single panic attack since finding his peace within.
Ten years later, he is still 100% on track and happy. He tells me that he believes that his substance abuse was a primary factor and now having a consistent personality without the mood changes from chemicals has been a huge thing for him.