Originally Posted by FBinNY

Probably the most annoying problem to diagnose on a bike is clicking or ticking synchronous to pedal rotation. There are so many possibilities, and all too often the noise doesn't originate anywhere near the cranks. I've seen it be a hub, headset or saddle problem, so you can see how this can be a nightmare.

That said start with the most basics, and do the simplest first. Eliminate the pedals by trying another pair. If that solves the problem, replace your originals and see if it's still OK. Often the type of noise you describe comes from the pedal/crank thread and simply removing and replacing pedals solves it. Sometimes adding a pedal washer prevents the clicking from returning better than without.

After the pedals, and a basic check of crank tightness it gets more complicated, so if it isn't the pedals, post the specifics of your crank and BB, and I or others will take through some of the next tier of possibilities.