Your profile doesn't indicate where you live nor do you describe your climbing experience. If you live in Florida, you're probably hosed. If you live in Colorado, no sweat I would think. From some of the responses I would think you need to be very comfortable climbing 10+% in the gearing you propose. If not, you'll probably suffer.

Of course depending upon trainer calibration, etc., you might be able to spin up at 12 mph. when you're done, post stats and pictures.