Originally Posted by
dddd
Well, yeah, but any frame's reliability comes down to a builder's quality-control and testing, and this frame was never tested with that hole in perhaps the most highly-stressed location in the entire frame.
The R&D will be at the new owner's expense you could say.
The dropouts are pretty beefy, but if the OP is concerned a screw can be threaded and lock tighted in that hole.
Brad