I hesitate to bring up physiology and genetics - a similar thread on the 41 dragged on 13 pages and led to charges of racism and stuff - and all wedgies are racists (j/k) - but that might influence ones choice of ride.

Last time I was checked. By CV fitness was 80% of my age, my strength was 50%, but my flexibility was 4%. I just don't do so well with road bikes. Bents work better for me.