I do it all the time, but Chombi is right; it often depends on the frame.
I tried it with a Schwinn Aluminum 564 and darn near lost a finger.
I've done it on one Cannondale, and if she gets a rear flat, she'll have to use a cell phone.
An aluminum Centurion was pretty difficult, also.

Most steel frames, especially the larger ones, accommodate the extra width with little more than some extra effort.

The hazards are: misalignment, chain rub on the smaller cogs, knuckle-busting when removing or installing the rear wheel, and sometimes the dish. I've never had the misalignment problem or the dish problem, only had chain rub on an older carbon frame, but have pinched a few fingertips. I'm serious in that you can easily nip off the end of a finger in one of those aluminum frames, or simply get it stuck in there, and you'll not get it out with the remaining unstuck hand.