Gain ratios don't do
anything to make gearing more portable between wheel sizes than gear inches. For all we know, the OP could be using the same length cranks on both bikes.
As for the original question, and partly as a counterpoint to Doohickie's post

, if your weight is high enough to slow you down, you may consider a lower gearing for that reason. Similar to the way that heavy studded tires will lop off speed and strain your knees if you try to use the same gearing as otherwise.