The only problem with 26” wheels on a road bike is the tires. Many tires in 26” seem to me to be more suitable for use on the family tractor. Fast roads tires are less common in 26” but they are available. I have had good luck with Conti Sport Contact 26x1.6”. They seem to be fast and comfortable. Vittoria Randonneur Pro 26x1.5” should also be good. There are more, but I am not familiar with all of them.