Ugh, yeah. I almost got taken out by a pothole the other day.

Big sucker that I didn't see because I was riding at night at about 27mph on a dark road under trees with a 1 watt headlamp.

Thing almost knocked me off the bike, it drove the seat into my sensitive areas, and I almost went off the road afterward.

Harder impact than ANYTHING I've hit while mountain biking (not counting things after I've fallen).