I run my tires at 100 psi. I have 2 flats in 100 miles on the original rubber (Bontrager Race X-Lite tires) then no more until I had to change at 1000 miles, 1 flat with Continential GP3000 in 1000 miles (I had to change at 1000 miles as threads were coming through - very disappointing). I now run Vittoria Rubino Pro's and so far no flats in 600 miles (also limited wear!)