I agree with T-Mar, in their intended application Biopace work well and the general concept of non-round chainrings is very well accepted in cycling. There's no reason to not trust it.

Back in the day our #1 complaint from customers is that they'd bounce in saddle at high rpm, those customers were racers and many simply changed out the big Biopace ring for a round ring. In subsequent years Shimano toned back the Biopace effect, I think the new rings were marked as Biopace II and were more round.