For me, I have always had a negative feeling towards the Biopace. There is no logical explanation for this. That said, I recently started riding a triple Biopace rig, a Gary Fisher "Hybrid" that I picked up recently.
Though the "Hybrid" does not look or feel "vintage" to me, it is a treat to ride. Also, I have been consciously considering the Biopace performance as I ride. So far, I like it but to know for sure that it is the ring design I like is tough to say. I would have to swap out crank rings and then ride. My guess is there will not be a huge difference, but you never know.
Either way, the Gary Fisher will remain as issued and "as found". I really like riding it.
As for the Durham, I owned a Motobecane Mirage fitted with one a few years ago. Actually, I got rid of the bike last Fall. Anyway, at any rpm over slow would cause the bicycle to bounce a bit...
I really did
not like riding the Motobe!