Not in my experience. I've got tubes in my tool box that are several years old and I've not found a sealed tube of quality vulcanizing fluid, i.e. Rema, that had dried out. The point is to buy good patch kits, not the cheapest ones you can find.

There are several reasons. First, vulcanizing fluid isn't rubber cement. In the case of the above mentioned Remas, the vulcanizing fluid and the patches are a 2 part system. The patch is coated with one compounds that is activated by another compound in the fluid. When combined, they form not just an adhesive bond but a chemical bond. The patch material becomes part of the tube rather than just being stuck to it.

Second, once tubes of vulcanizing fluid have been opened, they can dry out. Buying a $2 tube of vulcanizing fluid once a year makes much more sense than buying large can of fluid and having it dry out, unless you are repairing hundreds of patches per year. I repair a lot of punctures but a large can of fluid makes little sense for even me.

There is also the problem of getting the fluid into a small bottle. It's not going to be easy since the fluid is rather thick. Application from a bottle would be difficult as well. I apply the fluid from the tube directly so that I don't contaminate the fluid and compromise the patch job.