I've got decent wheels on my bike, not high end but decent (Bontrager Race Lites) with a 24 spoke arrangement. After about 14 months and around 7-8K miles the front developed a pronounced out of true which I had fixed at my LBS. About a month later out of true again, back to LBS. Months later same thing but I trued it this time, two weeks later, ditto. The rear is still perfect.

What's up with this? Is there a loctite type compound to keep the spoke nipples from backing off? If so, why don't the factories use it? When the wheel gets out of true, it seems to develop rapidly and in from ride to the next and the wheel gets quite out, on the order of a 1/4" or a little more.