The old favourite is Ultegra hubs to Mavic Pro rims. But times change. Probably better rims about now but that Ultegra hub is still pretty good. I went with 105 hubs and Mavic CXP33 rims and 36 spokes. I am a lightweight but those wheels will hold for some of the "Lighter" Clydes. Very strong tight wheels and I would say indestructible. The "Lacing" pattern on the wheels can have an affect on ridability and most handbuilts have the spokes crossing 2 or 3 other spokes. Gives a more compliant ride and does not affect the Strength of the wheel.