I run 2.35" BA's on my Surly LHT. This bike is used for commuting and touring, so it's loaded about 99% of the time I ride it. The rolling mass is nice on flats and downhill but can be a bear on hills. For out of the saddle climbing the amount of tire bounce does steal power but that is a trade off I am willing to make. The ability to ride over the pot holes and curbs and not have your teeth jarred is worth it. The LHT is the 1960's Caddy of my bike fleet, so comfort is key. I usually run 35 psi front, 45 psi rear. Anything higher really ruins the 'balloon' effect for me.

I recently converted them to 'ghetto tubeless' and managed to save about 0.8 lbs of inner tube weight. Even better now.