Old 02-03-13 | 03:05 PM
  #62  
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GeorgeBMac
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Originally Posted by Bikey Mikey
Don in Austin

I'm unsure if you interpreted my stating "has a similar effect" as meaning lowering risk of heart attack or not. What I meant in saying "similar effect" was in the lowering of cholesterol. With Zetia+Statin, you don't need as high a dosage of the Statin if you used the Statin alone.

You can find lots of articles stating some drug treatment is effective and you can find probably as many stating a drug treatment isn't. We must remember, even though statistically it may be effective, we are individuals and some may not benefit at all. We also are going on what we know now and that may change. Science and medicine change with new discoveries and new data. In the sciences, you know things aren't absolute and that what you know now may be not correct in the future.
Yes, it's true that Zetia (Ezetimibe + Simvastatin) lowers cholesterol more than the statin by itself.

But, in the ENHANCE trial, they were shocked to find out that adding Ezetimibe to Simvastatin did nothing to improve atherosclerosis. In fact, it made it worse! To the best of my knowledge, they still haven't figured out why and they're still scratching their heads...

But this was a major financial blow to Merck who had already made many billions selling this drug.
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