You're going to laugh at the problems I have with bike clothes.
I ride a recumbent so I get no tushie discomfort at all but, with my feet higher than my butt, I tend to drop things out of my pockets. Last week, I lost my cell phone but a nice lady found it and made the effort to figure out how to get it back to me. She wouldn't accept a reward either. In the past I've also dropped my car keys but, so far, I've always gotten them back. If I don't change my ways I may not be so lucky forever.
I've got some recumbent shorts that have zippers for the pockets but I forget to zip them. I also have some recumbent specific jerseys that have pockets on the sides so I don't have to lean back on lumpy tools and such.