My limits are Gainesville to the north and Naples to the south, about a 2.5 hour radius. There are plenty that fall into this area.
Tallahassee (4 hours) and Miami (4.5-5 hours) are the furthest cities I've driven to on race weekends. Kind of have no desire to do that anymore... my days of racing in Daytona Beach one weekend then Jacksonville the next are over.