I've struggled with shoulder and neck pain due to poor posture. I had a great professional fit when I ordered my custom Indy Fab four years ago. For some reason two years ago I thought I needed to make some adjustments. Right after that is when the pain started. Eventually (I'm not always the brightest or fastest when it comes to figuring things out) I realized I needed to get "back to where I was." Took the bike back to the shop that ordered it for me. They pulled their records and set it up the way it was on the day it was delivered. Since then no pain. It turns out that the pain was due to my shoulders and neck being tense from being too hunched. I had moved the seat forward, put on 42mm bars in place of the 44s, and raised the bars slightly. I was just too cramped in that postion. Once I was back where I belonged my neck and shoulders could relax and fall into a more natural position.