Liquid nitrogen or some type of rapid freezing agent, a hammer used to be popular for thieves in Boston in the 1980s and early 1990s. It would just shatter the lock mechanism.
Also the ever popular van pulls up, open the door, a small hydraulic jack or diamond saw, and bike is gone.
If someone wants your high-end bike, they will get it. If you are that concerned (hey, even paranoids have enemies!), the best insurance is to keep the bike inside in a secure area at your work or home.
My understanding is a lot of bike thefts were for the components - is this still the case?