Ride around Ann Arbor on the northeast side. Broadway / Plymouth Rd are challenging, as is Geddes Road and Huron Parkway.
On the Zoo-de-Mac, the key is to take your time at the start. The third hill can surprise you. I only made it to the Good Hart 1/2 way point, because I got 3 flats in quick succession, but my friends who went the distance said if the wind comes from the east after the Pellston Airport, your screwed.
Good luck!