Mine has the Ortlieb L Office bag (laptop, papers, tablet, etc) on one side, and a cheapo Ibera pannier opposite. The top rack is either empty or has my Polar Bear soft cooler strapped to it. Also have a Handlebar bag as well that I put my wallet, keys, tissue, etc in.
I do this everyday that I commute (26Miles RT). Been trying to get it where I can unload it Tuesday-Friday, but have not been successful. The Ortlieb bag gets used even on days that I use the truck for commute.
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