Originally Posted by
HillRider
Assuming you don't have one of the 10-speed only Shimano hubs (Dura Ace 7800 hubs and it's contemporary Dura Ace and Ultegra wheelsets) the cassettes will interchange between the wheels and your concept will work.
Be aware that you might have to do some minor adjustments to the limit screws and cable tension after each change as even "interchangeable" hubs have very slight dimensional difference.
Yes, cassette position with respect to the face of the locknut (inside of the dropout) varies hub to hub, and among mixed cassettes (brand, or # of gears). If you have access to shim stock in assorted thicknesses, you can make thin spacers to put behind cassettes, bringing the outer sprockets to an exact distance from the dropout, therey eliminating any fine tuning on wheel changes.
I've done this to team racing wheels for almost 40 years (going back to F/W days) so the entire team could work with a single pool of wheels without any tuning. I also measured all chains to accommodate the widest gearing to avoid any nasty surprises when wheels and cassettes were switched on the fly.