Maybe I missed it. But you may be having a "pressure sore" in the saddle area. Bacteria, padding, lack of lubricant, etc. etc. etc. can all contribute by making things worse. But if the pressure point isn't relieved, the sore will certainly return. I dealt with a pressure sore for a couple years, thinking it was my saddle causing the problem. After about 5 different saddle choices, I concluded it wasn't the saddle. A friend of mine (who happens to be a bike fitter) suggested I might have a leg length issue- in essence, a shorter legging causing more pressure on one side. So I tried a leg length shim. And voila! pressure sore gone. Just a thought... oh, and I got my shim at bikefit.com