There's a new forum "fitting your bike" which appears below this one in the Bike Forums menu. You may want to try there.

Obviously your saddle position influences the way your weight is distributed on the bike, and if your triceps are getting tired (which is a new one on me, certainly) you are either putting too much weight on your hands, or holding the bars in a death grip, or both. But there are other things that influence it. Counter-intuitvely, lowering the handlebars is often a recipe for reducing the weight borne by the hands. It shifts weight off the seat over the pedals, one is effectively 'flying over the bike' in the standard roadie position, and both seat and hands are relieved of some pressure.

If you're experimenting with saddle position remember that if you move it right forward you will need to raise it a little, and lower it if moving it right back, to compensate for the change in distance from saddle to pedal.