Alright, last question before I place my order

I don't have any knee pain as some of you have brought up. This is my first fixie and I'm a little wary about jumping from 16 to 18 since it's a 9 inch difference. Is this too much of a difference?
Although I'm sure this varies among people, how much will a 1 tooth increase change my cadence? How much does it change yours?
Thanks again guys.